Searchable abstracts of presentations at key conferences in endocrinology

ea0081p427 | Pituitary and Neuroendocrinology | ECE2022

Long-term Tolvaptan therapy in the treatment of SIAD in Elderly- A case report with challenging cytochrome P 450 drug interactions

Madhurya Kethireddi Keerthi , Babu Parthasarathy Sathish

Background: Chronic SIAD with its disabling impact is challenging to manage in elderly patients as fluid restriction or demeclocycline often has a limited success. Tolvaptan is a novel selective antagonist of vasopressin receptor (V2R) which is safely used in patients with SIAD and other conditions with hypervolemia. We report a case of longest Tolvaptan use with significant challenges amongst our case series which we had previously publishedMethod: A Ca...